President’s Emergency Plan for AIDS Relief (PEPFAR’s) response to the millions of children impacted by HIV/AIDS was to designate 10% of its budget to securing their futures, making it the leading supporter of programs reaching orphan and vulnerable children (OVC) programs globally. This article describes the evolution of PEPFAR’s OVC response based on programmatic lessons learned and an ever growing understanding of the impacts of HIV/AIDS. In launching this international emergency effort and transitioning it toward sustainable local systems, PEPFAR helped establish both the technical content and the central importance of care and support for OVC as a necessary complement to biomedical efforts to end the HIV/AIDS epidemic.

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Case management is a standard practice in the United States for the effective care of people living with HIV and AIDS (PLHA); however, application of this approach in developing countries has not been demonstrated. Although great advances have been made in Africa to increase PLHA’s access to HIV services, care and support systems often remain fragmented. In September 2004, CARE International initiated a case management program in health facilities in Rwanda designed to enhance linkages between clinical and non-clinical services for PLHA.

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Sampling methods to study street children often rely on convenience approaches. Respondent-driven sampling (RDS) is a relatively new methodology for sampling hard-to-reach populations utilizing peer-driven recruitment. It includes both field and analytical procedures to account for non-random recruitment patterns and generates statistically valid samples. This article describes RDS and assesses its effectiveness to recruit a diverse sample of street children, defined as children aged 10–17 years who engage in economic activity on the street in Tirana, Albania.

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Addressing the psychosocial needs of vulnerable children and youth is viewed increasingly as a priority of humanitarian programs, particularly in Africa, where the scale of the problem necessitates community-based solutions. This quasi-experimental study tested a model of adult mentorship and support to improve psychosocial outcomes among youth-headed households in a rural area of Rwanda. Two rounds of data were collected from youth who served as heads of their households.

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Objective To examine the level of depressive symptoms and their predictors in youth from one region of Rwanda who function as heads of household (ie, those responsible for caring for other children) and care for younger orphans.

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A consistent theme in the literature on interventions for orphans and vulnerable children is the need for community-based care. However, a number of socio-cultural factors may impede community response. In this study, mixed methods are used to elucidate community-level barriers to care for orphans and vulnerable youth in Rwanda. Data from a large survey of youth heads of household on perceptions of marginalization from the community and the factors predicting that marginalization are considered in light of additional data from a survey of adults who volunteered to mentor these youth and focus groups with both community adults and youth heads of household.

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There is concern that orphans may be at particular risk of HIV infection due to earlier age of sexual onset and higher likelihood of sexual exploitation or abuse; however, there is limited empirical evidence examining this phenomenon. Utilizing data from 1694 Black South African youth aged 14–18, of whom 31% are classified as orphaned, this analysis explores the relationship between orphan status and sexual risk. The analysis found both male and female orphans significantly more likely to have engaged in sex as compared to non-orphans (49% vs. 39%).

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Child and youth care workers (CYCWs) are a crucial and growing component of South Africa’s national response to HIV and AIDS and other problems affecting children and families. CYCWs use the community-centred Isibindi model of care to reach the most vulnerable with key services including psychosocial, health, economic and education support. Understanding how to support retention in the CYCW workforce is vital to programme quality and sustainability.

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Effective strategies for HIV prevention among adolescent orphans and vulnerable children (OVC) in South Africa, particularly girls and young women, are critically needed. To date, adolescent-only educational and behavioral interventions have underpinned prevention efforts with mixed success. Addressing a broader array of adolescent risk factors may help to lower HIV prevalence in this priority population. Let’s Talk is a structured adolescent HIV prevention intervention that goes beyond standard knowledge and skills-based programming to address family dynamics and mental health.

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Many children in South Africa live outside of parental care, due to orphanhood, parental labour migration, unemployment, and for other reasons. Family members and other adults thus play an important role in providing substitute care. Non-parental caregivers have been found to experience high levels of psychological distress and burden, potentially leading to poor outcomes for children. The present analysis examines whether these and other potential risk factors are associated with caregiver-perpetrated physical aggression towards adolescent girls living outside of parental care in the Free State province.

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Early bereavement is common in South Africa, where almost a fifth of children have lost a parent and many more have experienced the death of another family member or friend. However, little is known about young people’s psychological responses to loss in this setting.

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Almost one-fifth of children in South Africa have lost a parent; many have experienced multiple losses. Bereaved children are at increased risk for psychological health problems including maladaptive grief and depression. Despite the scale of need, evidence for effective psychological support services is limited.

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Children and adolescents affected by HIV are at elevated risk for depression, yet research on related interventions in this population is scarce in sub-Saharan Africa. This study sought to examine the effects of interpersonal psychotherapy for groups (IPTG) on depressive symptomology among orphaned and vulnerable adolescents in South Africa—home to the world’s largest HIV epidemic.

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Community-based care and support programmes for orphaned and vulnerable children (OVC) and their families are a critical component of HIV prevention, care and treatment efforts worldwide. Addressing the challenges that confront programme evaluators in these contexts can help promote robust evidence for effective programming.

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Home visiting is a popular component of programs for HIV‐affected children in sub‐Saharan Africa. Many programs are staffed by volunteers whose training and compensation is minimal, raising questions about whether investing in paraprofessional workforce development might yield measurable gains in beneficiaries’ well‐being.

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Cash transfers for low‐income families are an effective investment in children’s health and well‐being. Identifying ways to increase social grant uptake among orphans and vulnerable children and their families in South Africa is therefore a priority. Home visitors may be particularly well‐positioned to connect families with the highest grants for which they are eligible.

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HIV counseling and testing underpin sustainable epidemic control, and international guidelines call for all children in generalized epidemic settings, such as South Africa, to be tested routinely. Identifying effective strategies for expanding pediatric uptake of HIV counseling and testing services is therefore critical.

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Adolescent orphans and vulnerable children (OVC) are at heightened risk of HIV infection. Effective preventive strategies are therefore urgently needed. While behavioural interventions are the cornerstone of HIV prevention, psychological interventions may also hold promise as part of a coordinated effort to decrease sexual risk‐taking.

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This brief describes the findings and program implications from a study designed to develop critical knowledge on “what works” to improve the well-being of children affected by HIV and AIDS.  Community-based home visiting, in which care workers provide a range of support services during regular visits to the child’s home, is an increasingly popular service delivery approach in South Africa. However, there is enormous variation in how home visiting programs are implemented.  The aim of the study is to evaluate the relative impact on child wellbeing of a range of home visiting models.

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Focusing on 13 program sites in KwaZulu-Natal, this report describes the support offered by Isibindi Child and Youth Care Workers (CYCWs) to beneficiary families as well as changes in key measures of children’s wellbeing over a two year period. We further examine differences in the provision of care and support services and changes in wellbeing between beneficiaries at high- and lower-functioning Isibindi sites, according to NACCW’s own site assessment process.

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